Navigating Clinical Trials: Essential Knowledge for Dermatologists-Clinical Trials in Atopic Dermatitis: Practical Considerations

Clinical Trials in Atopic Dermatitis: Practical Considerations

Video Transcription

Video Summary

The speaker discusses clinical trials in atopic dermatitis, emphasizing their importance in advancing treatment. Despite being the most common inflammatory skin condition, there's a strong need for better long-term disease control. The speaker highlights various drugs in late-stage trials and notes that even failed trials offer valuable insights into disease understanding and treatment pathways. They advocate for a systematic approach in conducting trials, starting small, building reputation, and ensuring thorough training of staff to handle diverse patient populations. Mechanistic studies are stressed for their role in understanding drug effects and the disease itself, with tape strips highlighted as a non-invasive method for biomarker analysis. The talk advises on best practices, including patient management, careful trial selection, and gradual expansion. Emphasizing a cautious, informed, and committed approach to research, the speaker underscores the broader impact of clinical and mechanistic studies in enhancing patient care.

Asset Subtitle

by Emma Guttman, MD, PhD, FAAD

Keywords

atopic dermatitis

clinical trials

disease control

biomarker analysis

patient management